{"id":14258,"date":"2021-06-23T16:57:28","date_gmt":"2021-06-23T21:57:28","guid":{"rendered":"https:\/\/cornflowerblue-rail-980953.hostingersite.com\/?p=14258"},"modified":"2021-06-23T16:57:28","modified_gmt":"2021-06-23T21:57:28","slug":"whats-new-in-nuclear-medicine-chinese-march-2021","status":"publish","type":"post","link":"https:\/\/staging-hub.acoredu.com\/zh-hans\/whats-new-in-nuclear-medicine-chinese-march-2021\/","title":{"rendered":"What’s new in Nuclear Medicine (Chinese) – March 2021"},"content":{"rendered":"

 <\/p>\n

\u4f7f\u7528\u5df2\u53d1\u8868\u7684\u5efa\u8bae\u884c\u4e2d\u671fPET\u8bc4\u4f30\u5728\u5f25\u6f2b\u6027\u5927B\u6dcb\u5df4\u7ec6\u80de\u7624\u4e2d\u7684\u4ef7\u503c\uff1aDeauville 5\u5206\u8bc4\u4f30\u548c\u0394SUVmax\u65b9\u6cd5\u7684\u6bd4\u8f83\u00a0<\/strong><\/span><\/h5>\n

Jan Rekowski, Andreas H\u00fcttmann, Christine Schmitz, Stefan P. M\u00fcller, Lars Kurch, J\u00f6rg Kotzerke, Christiane Franzius, Matthias Weckesser, Frank M. Bengel, Martin Freesmeyer, Andreas Hertel, Thomas Krohn, Jens Holzinger, Ingo Brink, Uwe Haberkorn, Fonyuy Nyuyki, Dani\u00eblle M.E. van Assema, Lilli Geworski, Dirk Hasenclever, Karl-Heinz J\u00f6ckel, and Ulrich D\u00fchrsen.<\/span>\u00a0<\/span><\/p>\n

J Nucl Med 2021; 62(1): 37-42.<\/span>\u00a0<\/span><\/p>\n

\u80cc\u666f<\/span>\uff1a<\/span>\u5728\u5316\u7597\u5468\u671f\u4e2d\u8fdb\u884c\u4e2d\u671f<\/span>18<\/span>F –<\/span>\u6c1f\u8131\u6c27\u8461\u8404\u7cd6<\/span>PET\/CT<\/span>\u4ee5\u8bc4\u4f30\u6cbb\u7597\u53cd\u5e94\uff0c\u5e76\u6307\u5bfc\u4fb5\u88ad\u6027\u6dcb\u5df4\u7624<\/span>(<\/span>\u5982\u5f25\u6f2b\u5927<\/span>B<\/span>\u7ec6\u80de\u6dcb\u5df4\u7624<\/span>(DLBCL))<\/span>\u7684\u8fdb\u4e00\u6b65\u6cbb\u7597\u3002\u76ee\u524d\u5bf9\u4e8e\u5206\u6790\u8fd9\u4e9b\u4e2d\u671f<\/span>PET<\/span>\u7684\u6cbb\u7597\u53cd\u5e94\u7684\u5efa\u8bae\u662f\u901a\u8fc7<\/span>Deauville<\/span>\u8bc4\u5206\u3002\u57fa\u4e8e\u75be\u75c5\u5c40\u90e8\u7684\u76f8\u5bf9\u653e\u5c04\u6027\u793a\u8e2a\u5242\u6444\u53d6\u5206\u914d\u4e94\u70b9\u8bc4\u5206\u7684\u4e00\u4e2a\u5206\u503c\uff1a<\/span>1<\/span>\u6ca1\u6709\u6b8b\u4f59\u6444\u53d6\uff0c<\/span>2<\/span>\u662f\u5c0f\u4e8e\u7eb5\u9694\u6444\u53d6\uff0c<\/span>3<\/span>\u662f\u6444\u53d6\u5c0f\u4e8e\u6216\u7b49\u4e8e\u809d\u810f<\/span>\uff0c4<\/span>\u662f\u67d0\u7a0b\u5ea6\u4e0a\u6444\u53d6\u5927\u4e8e\u809d\u810f<\/span>,<\/span>\u548c<\/span>5<\/span>\u662f\u6444\u53d6\u8fdc\u8fdc\u5927\u4e8e\u809d\u810f<\/span>\uff1b4<\/span>\u5206\u6216<\/span>5<\/span>\u5206\u88ab\u8ba4\u4e3a\u662f\u4e0d\u826f\u7684\u6cbb\u7597\u53cd\u5e94<\/span>\u3002Deauville<\/span>\u8bc4\u5206\u53ea\u9700\u8981\u4e2d\u671f<\/span>PET\/CT<\/span>\uff0c\u4f46\u5047\u9633\u6027\u66f4\u9ad8\uff0c\u56e0\u6b64\u4f4e\u4f30\u4e86\u6cbb\u7597\u53cd\u5e94\u3002\u6cbb\u7597\u53cd\u5e94\u4e5f\u53ef\u4ee5\u901a\u8fc7<\/span>\u0394SUVmax<\/span>\u6765\u8bc4\u4f30\uff0c<\/span>\u0394SUVmax<\/span>\u6bd4\u8f83\u7b2c\u4e00\u6b21<\/span>PET\/CT<\/span>\u548c\u4e2d\u671f<\/span>PET\/CT<\/span>\u4e2d\u5177\u6709\u6700\u9ad8\u653e\u5c04\u6027\u793a\u8e2a\u5242\u6444\u53d6<\/span>(SUVmax)<\/span>\u7684\u75c5\u53d8\u90e8\u4f4d<\/span>(\u0394SUVmax)<\/span>\uff1b\u6444\u53d6\u51cf\u5c11\u4e09\u5206\u4e4b\u4e8c\u6216\u66f4\u5c11\u88ab\u8ba4\u4e3a\u662f\u4e0d\u826f\u7684\u6cbb\u7597\u53cd\u5e94<\/span>\u3002\u0394SUVmax<\/span>\u65b9\u6cd5\u9700\u8981\u6cbb\u7597\u524d\u548c\u4e2d\u671f<\/span>PET\/CT<\/span>\uff0c\u4f46\u63d0\u4f9b\u4e0d\u53d7\u80cc\u666f\u6444\u53d6\u5f71\u54cd\u7684\u534a\u5b9a\u91cf\u8bc4\u4f30\u3002\u76ee\u524d\u5bf9\u8fd9\u4e24\u79cd\u65b9\u6cd5\u7684\u6bd4\u8f83\u7814\u7a76\u8f83\u5c11\uff0c\u9700\u8981\u8fdb\u4e00\u6b65\u7684\u7814\u7a76\u3002<\/span>\u00a0<\/span><\/p>\n

\u76ee\u7684<\/span>\uff1a<\/span>\u6bd4\u8f83<\/span>Deauville<\/span>\u8bc4\u5206\u548c<\/span>\u0394SUVmax<\/span>\u65b9\u6cd5\u5728\u8bc4\u4f30<\/span>DLBCL<\/span>\u6cbb\u7597\u53cd\u5e94\u4e2d\u7684\u4ef7\u503c<\/span>\u00a0<\/span><\/p>\n

\u65b9\u6cd5<\/span>\uff1a<\/span>\u91c7\u7528\u591a\u4e2d\u5fc3<\/span>PET<\/span>\u5f15\u5bfc\u6cbb\u7597\u4fb5\u88ad\u6027\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624<\/span>(PETAL)<\/span>\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u7684\u6570\u636e<\/span>\uff1a<\/span>\u8be5\u8bd5\u9a8c\u7814\u7a76\u4e86\u57fa\u4e8e\u4e2d\u671f<\/span>PET\/CT<\/span>\u53cd\u5e94<\/span>\uff0c<\/span>\u65b0\u8bca\u65ad\u7684\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624<\/span>(NHL)<\/span>\u7684\u6cbb\u7597\u9009\u62e9\u3002\u6240\u6709\u60a3\u8005\u5747\u63a5\u53d7\u76f8\u540c\u7684\u521d\u59cb\u5316\u7597\u65b9\u6848\u3002\u4e2d\u671f<\/span>PET\/CT<\/span>\u7ed3\u679c\u4e0d\u4f73\u7684\u60a3\u8005\u4e0e\u4e2d\u671f<\/span>PET\/CT<\/span>\u7ed3\u679c\u826f\u597d\u7684\u60a3\u8005\u63a5\u53d7\u4e86\u4e0d\u540c\u7684\u540e\u7eed\u6cbb\u7597<\/span>\uff1a<\/span>\u6700\u7ec8\u60a3\u8005\u7ed3\u679c\u4e0d\u53d7\u6cbb\u7597\u6539\u53d8\u7684\u5f71\u54cd\u3002\u6240\u6709\u60a3\u8005\u5747\u63a5\u53d7\u57fa\u7ebf\u548c\u4e2d\u671f<\/span>PET\/CT<\/span>\u68c0\u67e5\uff0c\u4e2d\u671f\u626b\u63cf\u5728\u7b2c<\/span>2<\/span>\u4e2a\u5316\u7597\u5468\u671f\u540e\u81f3\u5c11<\/span>10<\/span>\u5929\u8fdb\u884c\u3002<\/span>\u00a0<\/span><\/p>\n

\u4f7f\u7528<\/span>\u0394SUVmax<\/span>\u65b9\u6cd5\u8bc4\u4f30\u4e2d\u671f<\/span>PET\/CT<\/span>\u626b\u63cf<\/span>\uff1a<\/span>\u5982\u679c<\/span>SUVmax<\/span>\u964d\u4f4e\u8d85\u8fc7<\/span>2 \/ 3<\/span>\u6216\u6444\u5165\u7684\u91cf\u662f\u751f\u7406\u6027\u7684\uff0c\u5219\u8ba4\u4e3a\u53cd\u5e94\u826f\u597d\u3002\u56de\u987e\u5206\u6790\uff0c\u8fd9\u4e9b\u626b\u63cf\u4e5f\u8fdb\u884c\u4e86<\/span>Deauville<\/span>\u8bc4\u5206\u8bc4\u4f30\uff0c\u8bc4\u5206\u4e3a<\/span>1<\/span>\u5230<\/span>3<\/span>\u5206\u4e3a\u53cd\u5e94\u826f\u597d\u3002\u4f5c\u8005\u4f7f\u7528<\/span>Spearmans<\/span>\u7b49\u7ea7\u76f8\u5173\u7cfb\u6570\u6765\u5206\u6790\u4e24\u79cd\u65b9\u6cd5\u4e4b\u95f4\u7684\u5173\u8054\uff0c<\/span>Kaplan-Meier<\/span>\u66f2\u7ebf\u6765\u5206\u6790\u7ed3\u679c\u5dee\u5f02\uff0c<\/span>AUC<\/span>\u7528\u4e8e\u9274\u522b\u80fd\u529b\u7684\u6bd4\u8f83<\/span>\u3002<\/span>\u00a0<\/span><\/p>\n

\u7ed3\u679c<\/span>\uff1a<\/span>\u7eb3\u5165<\/span>596<\/span>\u4f8b\u60a3\u8005\u3002\u6839\u636e<\/span>\u0394SUVmax92<\/span>\u4f8b\u8bc4\u4e3a\u53cd\u5e94\u4e0d\u826f<\/span>(<\/span>\u6444\u53d6\u51cf\u5c11<\/span>2 \/ 3<\/span>\u6216\u66f4\u5c11<\/span>)<\/span>\uff0c\u5176\u4e2d<\/span>29<\/span>\u4f8b\u4ec5\u5728\u4e2d\u671f<\/span>PET\/CT<\/span>\u4e0a\u6709\u751f\u7406\u6c34\u5e73\u7684\u6444\u53d6\uff0c\u56e0\u6b64\u88ab\u91cd\u65b0\u5f52\u7c7b\u4e3a\u53cd\u5e94\u826f\u597d<\/span>\uff0c\u0394SUVmax<\/span>\u8bc4\u4e3a\u53cd\u5e94\u4e0d\u826f\u7684\u6709<\/span>63<\/span>\u4f8b\u3002\u6839\u636e<\/span>Deauville<\/span>\u8bc4\u5206<\/span>\uff0c270<\/span>\u4eba\u8bc4\u4e3a\u53cd\u5e94\u4e0d\u826f\u3002\u4e24\u79cd\u65b9\u6cd5\u4e4b\u95f4\u7684\u4e00\u81f4\u6027\u4e3a<\/span>63%<\/span>\uff0c\u8d85\u8fc7<\/span>1 \/ 3<\/span>\u7684\u60a3\u8005\u6839\u636e<\/span>Deauville<\/span>\u8bc4\u4e3a\u53cd\u5e94\u4e0d\u826f\uff0c\u4f46<\/span>\u0394SUVmax<\/span>\u8bc4\u4e3a\u53cd\u5e94\u826f\u597d\u3002<\/span>\u00a0<\/span><\/p>\n

\u4e24\u5e74\u540e\u65e0\u4e8b\u4ef6\u751f\u5b58\u7387\u4e3a<\/span>71%<\/span>\u3002\u4e24\u79cd\u65b9\u6cd5\u7684\u9274\u522b\u80fd\u529b\u90fd\u8f83\u5dee\uff0c\u4f46<\/span>\u0394SUVmax<\/span>\u65b9\u6cd5\u7684\u9274\u522b\u80fd\u529b\u9ad8\u4e8e<\/span>Deauville<\/span>\u8bc4\u5206\u3002<\/span>Kaplan-Meier<\/span>\u65e0\u4e8b\u4ef6\u751f\u5b58\u66f2\u7ebf\u663e\u793a\uff0c<\/span>\u0394SUVmax<\/span>\u6bd4<\/span>Deauville<\/span>\u8bc4\u5206\u5728\u53cd\u5e94\u826f\u597d<\/span>\/<\/span>\u53cd\u5e94\u4e0d\u826f\u7ec4\u4e2d\u7684\u5dee\u5f02\u66f4\u663e\u8457\u3002<\/span>Deauville<\/span>\u8bc4\u5206\u7684\u7075\u654f\u5ea6<\/span>(52.5% vs 24.6%)<\/span>\u9ad8\u4e8e<\/span>\u0394SUVmax<\/span>\u65b9\u6cd5\uff0c\u7279\u5f02\u6027<\/span>(57.5% vs 88.8%)<\/span>\u4f4e\u4e8e<\/span>\u0394SUVmax<\/span>\u65b9\u6cd5\uff0c\u56e0\u6b64\u5047\u9633\u6027\u7387\u8f83\u9ad8\u3002\u5728\u6240\u6709\u7ed3\u679c\u4e2d\uff0c<\/span>\u0394SUVmax<\/span>\u65b9\u6cd5\u7684\u9633\u6027\u9884\u6d4b\u503c\u9ad8\u4e8e<\/span>Deauville<\/span>\u8bc4\u5206\uff0c\u9634\u6027\u9884\u6d4b\u503c\u4f4e\u4e8e<\/span>Deauville<\/span>\u8bc4\u5206\u3002<\/span>\u00a0<\/span><\/p>\n

\u8ba8\u8bba<\/span>\uff1a<\/span>\u5148\u524d\u7684\u7814\u7a76\u8868\u660e\uff0c\u4e2d\u671f<\/span>PET\/CT<\/span>\u7684<\/span>\u0394SUVmax<\/span>\u65b9\u6cd5\u5206\u6790\u80fd\u9884\u6d4b\u603b\u751f\u5b58\u7387\uff0c\u800c<\/span>Deauville<\/span>\u8bc4\u5206\u5047\u9633\u6027\u7387\u8f83\u9ad8\u3002\u5728\u672c\u7814\u7a76\u4e2d\uff0c<\/span>\u0394SUVmax<\/span>\u65b9\u6cd5\u6bd4<\/span>Deauville<\/span>\u8bc4\u5206\u5177\u6709\u66f4\u597d\u7684\u9274\u522b\u80fd\u529b\uff0c\u5e76\u4e14\u518d\u6b21\u8bc1\u660e\u4e86<\/span>Deauville<\/span>\u8bc4\u5206\u5177\u6709\u8f83\u9ad8\u7684\u5047\u9633\u6027\u7387\u3002\u56e0\u6b64\uff0c\u7528<\/span>Deauville<\/span>\u8bc4\u5206\u8bc4\u4f30\u4e2d\u671f<\/span>PET\/CT<\/span>\u66f4\u6709\u53ef\u80fd\u63d0\u793a\u60a3\u8005\u9700\u8981\u66f4\u79ef\u6781\u7684\u6cbb\u7597\uff0c\u5c3d\u7ba1\u4ed6\u4eec\u53ef\u80fd\u786e\u5b9e\u5bf9\u76ee\u524d\u7684\u4f4e\u6bd2\u6027\u548c\u4f4e\u6210\u672c\u6cbb\u7597\u53cd\u5e94\u826f\u597d\u3002<\/span>\u00a0<\/span><\/p>\n

\u7ed3\u8bba<\/span>\uff1a<\/span>\u5728\u540c\u65f6\u8fdb\u884c\u4e86\u57fa\u7ebf\u548c\u4e2d\u671f<\/span>PET\/CT<\/span>\u7684\u60c5\u51b5\u4e0b\uff0c\u57fa\u4e8e\u65e9\u671f\u4ee3\u8c22\u53cd\u5e94<\/span>\uff0c\u0394SUVmax<\/span>\u65b9\u6cd5\u53ef\u80fd\u5728\u6cbb\u7597\u51b3\u7b56\u4e2d\u63d0\u4f9b\u66f4\u597d\u7684\u9884\u540e\u4ef7\u503c\uff0c\u56e0\u4e3a\u4e0e<\/span>Deauville<\/span>\u8bc4\u5206\u76f8\u6bd4\uff0c<\/span>\u0394SUVmax<\/span>\u6cd5\u7684\u5047\u9633\u6027\u7387\u66f4\u4f4e\u3002<\/span>\u00a0<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u6bd4\u8f83\u752818F-FDG PET\u4e0e99mTc\u9aa8\u663e\u50cf\u8bc4\u4f30\u9aa8\u75c5\u53d8\u5bfc\u81f4\u8f6c\u79fb\u6027\u4e73\u817a\u764c\u6cbb\u7597\u7684\u4e34\u5e8a\u76f8\u5173\u5dee\u5f02\u3002\u00a0<\/strong><\/span><\/h5>\n

Suzanne C. van Es, Ton Velleman, Sjoerd G. Elias, Frederike Bensch, Adrienne H. Brouwers, Andor W.J.M. Glaudemans, Thomas C. Kwee, Marleen Woltman-van Iersel, John H. Maduro, Sjoukje F. Oosting, Elisabeth G.E. de Vries, and Carolina P. Schr\u00f6der.<\/span>\u00a0<\/span><\/p>\n

J Nucl Med 2021; 62(2): 177-83.<\/span>\u00a0<\/span><\/p>\n

\u80cc\u666f<\/span>\uff1a<\/span>\u5728\u6240\u6709\u8f6c\u79fb\u6027\u4e73\u817a\u764c\u7684\u60a3\u8005\u4e2d\uff0c\u6709\u534a\u6570\u60a3\u8005\u9aa8\u662f\u7b2c\u4e00\u4e2a\u8f6c\u79fb\u90e8\u4f4d\u3002\u76ee\u524d\uff0c\u56fd\u5bb6\u7efc\u5408\u764c\u75c7\u7f51\u7edc<\/span>(NCCN)<\/span>\u63a8\u8350\u5168\u8eab\u9aa8\u9abc\u626b\u63cf<\/span>(BS)<\/span>\u6765\u8bc4\u4f30\u9aa8\u8f6c\u79fb\uff0c\u5e76\u8003\u8651\u5c06<\/span>18<\/span>F –<\/span>\u6c1f\u8131\u6c27\u8461\u8404\u7cd6<\/span>PET (FDG-PET)<\/span>\u4f5c\u4e3a\u4e00\u79cd\u53ef\u9009\u7684\u8f85\u52a9\u68c0\u67e5\u3002\u5355\u72ec\u4f7f\u7528<\/span>BS<\/span>\u6709\u6f0f\u8bca\u6eb6\u9aa8\u8f6c\u79fb\u7684\u98ce\u9669\u3002\u867d\u7136\u6709\u6bd4\u8f83<\/span>BS<\/span>\u548c<\/span>FDG-PET<\/span>\u7684\u7814\u7a76\uff0c\u4f46\u5b83\u4eec\u6ca1\u6709\u6bd4\u8f83\u4e34\u5e8a\u610f\u4e49\u3002<\/span>\u00a0<\/span><\/p>\n

\u76ee\u7684<\/span>\uff1a<\/span>\u6bd4\u8f83\u8f6c\u79fb\u6027\u4e73\u817a\u764c<\/span>(MBC)<\/span>\u60a3\u8005\u7684\u4e34\u5e8a\u7ed3\u679c\uff0c\u8fd9\u4e9b\u60a3\u8005\u5747\u5728\u63a5\u53d7<\/span>BS<\/span>\u540e\u8fdb\u884c\u589e\u5f3a<\/span>CT (ceCT)<\/span>\u548c\u6709<\/span>ceCT<\/span>\u7684<\/span>FDG-PET \u3002<\/span>\u00a0<\/span><\/p>\n

\u65b9\u6cd5\uff1a\u672c\u7814\u7a76\u7eb3\u5165\u4e86\u591a\u4e2d\u5fc3<\/span>IMPACT-MBC<\/span>\u4e2d\u65b0\u8bca\u65ad\u7684\u975e\u8fc5\u901f\u8fdb\u5c55\u7684<\/span>MBC<\/span>\u60a3\u8005<\/span>\u3002<\/span>\u6240\u6709\u60a3\u8005\u5747\u63a5\u53d7\u4e86\u57fa\u7ebf<\/span>BS\u3001FDG-PET\/CT<\/span>\u548c<\/span>ceCT<\/span>\u3002\u7531\u4e24\u540d\u653e\u5c04\u79d1\u533b\u751f\u548c\u4e24\u540d\u6838\u533b\u5b66\u4e13\u5bb6\u5bf9\u6240\u6709\u4e09\u79cd\u68c0\u67e5\u4e2d\u7684\u9aa8\u9abc\u75c5\u53d8\u8fdb\u884c\u8bc4\u4f30\u3002\u6cbb\u7597\u5efa\u8bae\u7531<\/span>5<\/span>\u540d\u80bf\u7624\u5b66\u5bb6\u7ec4\u6210\u7684\u5c0f\u7ec4\u5728<\/span>10<\/span>\u6b21\u4f1a\u8bae\u4e2d\u7684\u4e24\u6b21\u8ba8\u8bba\u4e2d\u63d0\u51fa\uff0c\u7b2c\u4e00\u6b21\u8ba8\u8bba\u57fa\u4e8e<\/span>BS+ceCT<\/span>\u800c\u7b2c\u4e8c\u6b21\u8ba8\u8bba\u57fa\u4e8e<\/span>FDG-PET\/CT+ceCT<\/span>\u3002\u5728\u4e24\u6b21\u8ba8\u8bba\u4e2d\uff0c\u63d0\u4f9b\u4e86<\/span>FDG-PET<\/span>\u53d1\u73b0\u7684\u6709\u5173\u5185\u810f\u5668\u5b98\u53d7\u7d2f\u7684\u4efb\u4f55\u76f8\u5173\u4fe1\u606f\u3002\u5f53\u5206\u6790\u8fd9\u4e9b\u5efa\u8bae\u65f6\uff0c\u4e34\u5e8a\u76f8\u5173\u7684\u5dee\u5f02\u5305\u62ec\u4e0d\u540c\u7684\u6cbb\u7597\u76ee\u7684<\/span>(<\/span>\u6839\u6cbb\u6027\u6216\u975e\u6839\u6cbb\u6027<\/span>)<\/span>\u548c\u4e0d\u540c\u7684\u7cfb\u7edf\u6216\u5c40\u90e8\u7597\u6cd5\u3002<\/span>\u00a0<\/span><\/p>\n

\u7ed3\u679c<\/span>\uff1a<\/span>\u5728\u7eb3\u5165\u7684<\/span>102<\/span>\u4f8b<\/span>MBC<\/span>\u60a3\u8005\u4e2d\uff0c<\/span>93<\/span>\u4f8b\u5728<\/span>ceCT\u3001BS<\/span>\u548c<\/span>\/<\/span>\u6216<\/span>FDG-PET<\/span>\u4e0a\u6709\u9aa8\u6027\u75c5\u53d8\uff0c<\/span>9<\/span>\u4f8b\u6709\u4e0d\u660e\u786e\u7684\u9aa8\u6027\u75c5\u53d8\u3002\u5728\u5176\u4ed6<\/span>84<\/span>\u4f8b\u60a3\u8005\u4e2d\uff0c\u53d1\u73b0\u4e86<\/span>3473<\/span>\u4e2a\u9aa8\u9abc\u75c5\u53d8<\/span>\uff1a<\/span>\u5355\u72ec<\/span>ceCT<\/span>\u53d1\u73b0<\/span>1004<\/span>\u4e2a\uff0c\u5355\u72ec<\/span>BS<\/span>\u53d1\u73b0<\/span>655<\/span>\u4e2a\uff0c\u5355\u72ec<\/span>FDG-PET<\/span>\u53d1\u73b0<\/span>2285<\/span>\u4e2a\u3002<\/span>FDG-PET<\/span>\u6bd4<\/span>ceCT<\/span>\u548c<\/span>BS<\/span>\u53d1\u73b0\u66f4\u591a\u7684\u9aa8\u9abc\u75c5\u53d8\uff0c\u800c<\/span>ceCT<\/span>\u6bd4<\/span>BS<\/span>\u53d1\u73b0\u66f4\u591a\u7684\u9aa8\u9abc\u75c5\u53d8\u3002<\/span>ceCT<\/span>\u5728<\/span>33<\/span>\u4f8b\u60a3\u8005\u4e2d\u53d1\u73b0\u4e86<\/span>299<\/span>\u4e2a\u75c5\u7076\uff0c\u800c\u8fd9\u4e9b\u75c5\u7076\u5728<\/span>BS<\/span>\u6216<\/span>FDG-PET<\/span>\u4e0a\u6ca1\u6709\u53d1\u73b0\u3002<\/span>\u00a0<\/span><\/p>\n

102<\/span>\u4f8b\u60a3\u8005\u4e2d\u6709<\/span>16<\/span>\u4f8b\u7684\u6cbb\u7597\u5efa\u8bae\u4e0d\u540c\uff0c\u56e0\u4e3a\u75c5\u7076\u662f\u5728<\/span>FDG-PET+ceCT<\/span>\u4e0a\u53d1\u73b0\u7684\uff0c\u800c\u5728<\/span>BS+ceCT<\/span>\u4e0a\u6ca1\u6709\u53d1\u73b0\uff0c\u5bfc\u81f4\u66f4\u7cfb\u7edf\u7684\u6cbb\u7597<\/span>(7<\/span>\u4f8b<\/span>)<\/span>\u6216\u6cbb\u7597\u76ee\u7684\u8f6c\u53d8\u4e3a\u59d1\u606f\u6027\u6cbb\u7597<\/span>(9<\/span>\u4f8b<\/span>)<\/span>\u3002\u5efa\u8bae\u8fdb\u884c\u7cfb\u7edf\u6cbb\u7597\u7684\u60a3\u8005\u6709\u5e7f\u6cdb\u8f6c\u79fb\u5e76\u7d2f\u53ca\u5185\u810f\uff0c\u800c\u6539\u53d8\u6cbb\u7597\u76ee\u7684\u7684\u60a3\u8005\u5176\u8f6c\u79fb\u8f83\u5c40\u9650\u3002\u5728<\/span>27<\/span>\u4f8b\u60a3\u8005\u4e2d\uff0c\u5efa\u8bae\u8fdb\u884c<\/span>FDG-PET<\/span>\u4ee5\u8fdb\u4e00\u6b65\u8bc4\u4f30\u75c5\u53d8\u3002<\/span>\u00a0<\/span><\/p>\n

\u8ba8\u8bba<\/span>\uff1aFDG-PET+ceCT<\/span>\u5bfc\u81f4<\/span>16<\/span>\u4f8b\u60a3\u8005\u7684\u6cbb\u7597\u5efa\u8bae\u53d1\u751f\u6539\u53d8<\/span>(9<\/span>\u4f8b\u4e3a\u59d1\u606f\u6027\u6cbb\u7597\uff0c<\/span>7<\/span>\u4f8b\u4e3a\u66f4\u7cfb\u7edf\u7684\u6cbb\u7597<\/span>)<\/span>\u3002\u867d\u7136\u4e4b\u524d\u6ca1\u6709\u7814\u7a76\u6bd4\u8f83<\/span>BS<\/span>\u548c<\/span>FDG-PET<\/span>\u5728<\/span>MBC<\/span>\u4e2d\u7684\u4e34\u5e8a\u76f8\u5173\u6027<\/span>\uff0c<\/span>\u6709\u7814\u7a76\u6bd4\u8f83\u4e86\u4ed6\u4eec\u53d1\u73b0\u9aa8\u8f6c\u79fb\u7624\u7684\u80fd\u529b<\/span>\uff1a<\/span>\u56de\u987e\u6027\u7814\u7a76\u8868\u660e<\/span>\uff0c<\/span>\u5982\u679c\u4e00\u5b9a\u8981\u505a<\/span>FDG-PET\uff0c<\/span>\u90a3\u4e48\u5c31\u4e0d\u9700\u8981\u505a<\/span>BS<\/span>\u4e86<\/span>\uff0c<\/span>\u56e0\u4e3a<\/span>BS<\/span>\u4e0d\u4f1a\u53d1\u73b0\u5728<\/span>FDG-PET<\/span>\u4e0a\u6ca1\u53d1\u73b0\u7684\u75c5\u53d8<\/span>\u3002<\/span>\u672c\u7814\u7a76\u518d\u6b21\u8bc1\u660e<\/span>FDG-PET<\/span>\u53d1\u73b0\u7684\u75c5\u53d8\u660e\u663e\u591a\u4e8e<\/span>BS<\/span>\uff0c\u5e76\u63d0\u793a\u4f18\u5148\u4f7f\u7528<\/span>FDG-PET+ceCT<\/span>\u800c\u4e0d\u662f<\/span>BS+ceCT<\/span>\u53ef\u80fd\u5bfc\u81f4\u4e34\u5e8a\u76f8\u5173\u7684\u6cbb\u7597\u53d8\u5316\u3002<\/span>\u00a0<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u75f4\u5446\u7684\u878d\u5408\u6210\u50cf\uff1a\u534a\u5b9a\u91cf(18F)\u6c1f\u8131\u6c27\u8461\u8404\u7cd6\u6b63\u7535\u5b50\u53d1\u5c04\u65ad\u5c42\u626b\u63cf\/\u78c1\u5171\u632f\u6210\u50cf\u65b9\u6cd5\u5728\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u7684\u4ef7\u503c\u3002\u00a0<\/strong><\/span><\/h5>\n

Ana Marija Franceschi, Kiyon Naser-Tavakolian, Michael Clifton, Osama Ahmed, Katarina Stoffers, Lev Bangiyev, Giuseppe Cruciata, Sean Clouston, and Dinko Franceschi.<\/span>\u00a0<\/span><\/p>\n

World J Nucl Med 2021; 20(1): 23-31.<\/span>\u00a0<\/span><\/p>\n

\u80cc\u666f<\/span>\uff1aPET\/MRI<\/span>\u6b63\u5728\u6210\u4e3a\u8bc4\u4f30\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u4e00\u79cd\u65b0\u624b\u6bb5\u3002\u65e9\u671f\u8bca\u65ad\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u662f\u6709\u6548\u6cbb\u7597\u4ee5\u7ef4\u6301\u751f\u6d3b\u8d28\u91cf\u548c\u5ef6\u7f13\u75be\u75c5\u8fdb\u5c55\u7684\u5173\u952e\u3002<\/span>18<\/span>F –<\/span>\u6c1f\u8131\u6c27\u8461\u8404\u7cd6<\/span>PET (FDG-PET)<\/span>\u8111\u6210\u50cf\u663e\u793a\u4e86\u5404\u79cd\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u7279\u5f81\uff0c\u5982\u7279\u5b9a\u7684\u8111\u53f6\u53d7\u7d2f\u548c\u4ee3\u8c22\u964d\u4f4e\u7684\u6a21\u5f0f<\/span>\uff1a<\/span>\u4f8b\u5982\u963f\u5c14\u8328\u6d77\u9ed8\u75c5<\/span>(AD)<\/span>\uff0c\u6d89\u53ca\u4e2d\u90e8\u989e\u53f6\u548c\u540e\u9876\u53f6\u76f8\u5e94\u7684\u4ee3\u8c22\u964d\u4f4e\uff1b\u989d\u989e\u53f6\u75f4\u5446<\/span>(FTD)<\/span>\u901a\u5e38\u6d89\u53ca\u989d\u53f6\u548c\u989e\u53f6<\/span>\uff1b<\/span>\u8def\u6613\u4f53\u75f4\u5446<\/span>(DLB)<\/span>\u5f71\u54cd\u6795\u53f6<\/span>\uff1b<\/span>\u6700\u540e\uff0c\u76ae\u8d28\u57fa\u5e95\u53d8\u6027<\/span>(CBD)<\/span>\u5f71\u54cd\u989d\u53f6\u548c\u9876\u53f6\uff0c\u5c3d\u7ba1\u56e0\u4e3a\u5176\u7f55\u89c1\u800c\u5c1a\u4e0d\u660e\u786e<\/span>\u3002FDG-PET<\/span>\u4e0e<\/span>MRI<\/span>\u7684\u7ed3\u5408\u53ef\u4ee5\u6539\u5584\u89e3\u5256\u5b9a\u4f4d\u548c\u7ea0\u6b63\u53ef\u80fd\u4f4e\u4f30\u5c40\u90e8\u4ee3\u8c22\u7684\u840e\u7f29\u533a\u57df\u3002<\/span>\u00a0<\/span><\/p>\n

\u76ee\u7684<\/span>\uff1a<\/span>\u8bc4\u4f30\u4e34\u5e8a\u75f4\u5446\u60a3\u8005<\/span>FDG-PET\/MRI<\/span>\u4e2d\uff0c\u8111\u7070\u8d28\u4f53\u79ef\u635f\u5931\u4e0e\u7279\u5b9a\u8111\u53f6\u4ee3\u8c22\u6444\u53d6\u51cf\u5c11\u4e4b\u95f4\u7684\u5173\u7cfb<\/span>\u00a0<\/span><\/p>\n

\u65b9\u6cd5\uff1a\u8fd9\u9879\u56de\u987e\u6027\u7814\u7a76\u7eb3\u5165\u4e86<\/span>89<\/span>\u540d\u60a3\u8005\uff0c\u8fd9\u4e9b\u60a3\u8005\u63a5\u53d7\u4e86\u4e34\u5e8a\u75f4\u5446\u7279\u5b9a\u7684\u8111<\/span>FDG-PET\/MRI<\/span>\u68c0\u67e5\u3002\u6240\u6709\u60a3\u8005\u968f\u540e\u6839\u636e\u4e34\u5e8a\u6570\u636e\u548c<\/span>FDG-PET\/MRI<\/span>\u4e0a\u7684\u4ee3\u8c22\u6444\u53d6\u548c\u76f8\u5e94\u7684\u4f53\u79ef\u635f\u5931\u8bca\u65ad\u4e3a\u7279\u5b9a\u4e9a\u578b\u75f4\u5446<\/span>(AD\u3001FTD\u3001DLB<\/span>\u6216<\/span>CBD)<\/span>\u3002\u4f5c\u8005\u4ece\u4e34\u5e8a\u6570\u636e\u4e2d\u6536\u96c6\u4e86\u5e38\u89c1\u75c7\u72b6\uff0c\u5b9a\u4e49\u4e3a\u51fa\u73b0\u5728<\/span>>50%<\/span>\u8be5\u79cd\u4e9a\u578b\u60a3\u8005\u4e2d\u7684\u75c7\u72b6\u3002\u4f7f\u7528\u897f\u95e8\u5b50<\/span>mMR 3T PET\/MRI<\/span>\u626b\u63cf\u4eea\u8fdb\u884c\u6210\u50cf\uff0c\u5e76\u7531\u4e24\u540d\u795e\u7ecf\u653e\u5c04\u5b66\u5bb6\u548c\u4e00\u540d\u6838\u533b\u5b66\u4e13\u5bb6\u4f7f\u7528<\/span>MIMneuro<\/span>\u548c<\/span>NeuroQuant<\/span>\u8f6f\u4ef6\u8fdb\u884c\u8bc4\u4f30\u3002\u5bf9\u4e8e\u4f4e\u4ee3\u8c22\u7684\u8bc4\u4f30\uff0c\u534a\u5b9a\u91cf<\/span>z<\/span>\u8bc4\u5206\u4f4e\u4e8e<\/span>-1.65<\/span>\u88ab\u5b9a\u4e49\u4e3a\u652f\u6301\u8be5\u4e9a\u578b\u8bca\u65ad\u7684\u4ee3\u8c22\u5f02\u5e38\u3002\u5bf9\u4e8e\u8111\u53f6\u4f53\u79ef\u635f\u5931\u7684\u8bc4\u4f30\uff0c\u4f53\u79ef\u4f4e\u4e8e\u540c\u9f84\u7684<\/span>5<\/span>\u767e\u5206\u4f4d\u88ab\u5b9a\u4e49\u4e3a\u5f02\u5e38\u4f53\u79ef\u635f\u5931\u3002\u4e09\u4f4d\u653e\u5c04\u79d1\u533b\u5e08\u4e0e\u4e34\u5e8a\u54a8\u8be2\u533b\u5e08\u8fdb\u884c\u8bca\u65ad\u8ba8\u8bba\u3002\u91c7\u7528<\/span>Pearson<\/span>\u76f8\u5173\u7cfb\u6570\u5206\u6790\u5404\u4e9a\u578b\u75f4\u5446\u7684\u4ee3\u8c22\u964d\u4f4e\u4e0e\u4f53\u79ef\u635f\u5931\u4e4b\u95f4\u7684\u7edf\u8ba1\u76f8\u5173\u6027\u3002<\/span>\u00a0<\/span><\/p>\n

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\u8ba8\u8bba\uff1a\u4f5c\u8005\u7814\u7a76\u4e86\u4f7f\u7528\u4f4e\u4ee3\u8c22\u548c\u4f53\u79ef\u635f\u5931\u7684\u534a\u5b9a\u91cf\u8111\u53f6\u7279\u5f02\u6027\u5206\u6790\u6765\u76f4\u63a5\u8bca\u65ad\u75f4\u5446\u4e9a\u578b\u7684\u53ef\u884c\u6027\u3002\u4ed6\u4eec\u7684\u7814\u7a76\u8868\u660e\u5728\u6240\u6709\u4e9a\u578b\u4e2d\u90fd\u8868\u73b0\u51fa\u4e86\u6b63\u76f8\u5173\u5173\u7cfb\uff0c\u5c3d\u7ba1\u5728\u6bcf\u4e2a\u4e9a\u578b\u4e2d\u8bca\u65ad\u4ef7\u503c\u548c\u7edf\u8ba1\u610f\u4e49\u5404\u4e0d\u76f8\u540c\u3002\u5728\u5c0f\u6837\u672c\u91cf\u7684\u80cc\u666f\u4e0b\uff0c\u8fd9\u4e9b\u65e9\u671f\u7ed3\u679c\u8868\u660e\uff0c\u8fd9\u4e9b\u534a\u5b9a\u91cf\u5de5\u5177\u6709\u63d0\u9ad8\u533b\u751f\u8bca\u65ad\u75f4\u5446\u4e9a\u578b\u4fe1\u5fc3\u7684\u6548\u7528<\/span>\u3002<\/span>\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"  \u4f7f\u7528\u5df2\u53d1\u8868\u7684\u5efa\u8bae […]","protected":false},"author":3,"featured_media":13794,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[213],"tags":[],"class_list":["post-14258","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-213"],"yoast_head":"\nWhat's new in Nuclear Medicine (Chinese) - 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